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During a research analysis of some traditional herbal remedies for vitiligo Dr. Amala Raman and her PhD student Zhixiu Lin discovered that an extract of a particular plant stimulated the production of melanocytes in cell cultures. After few years the name of that particular extract was revealed to be piperine – the compound that gives black pepper its spicy, pungent flavor. This research was partly funded by vitiligo society.

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Every day a healthy immune system fights off an average of 10,000 mutant cells. Problems emerge when the immune system is not able to fight off these cells, allowing them to get a foothold and develop into a cancer. The characteristics of cancerous cells cause them to inhibit the proper regulation of the immune system.

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